Detalhe da pesquisa
1.
Complete biosynthesis of the potent vaccine adjuvant QS-21.
Nat Chem Biol
; 20(4): 493-502, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38278997
2.
Safety and efficacy of malaria vaccine candidate R21/Matrix-M in African children: a multicentre, double-blind, randomised, phase 3 trial.
Lancet
; 403(10426): 533-544, 2024 Feb 10.
Artigo
Inglês
| MEDLINE | ID: mdl-38310910
3.
Integrating network pharmacology and transcriptomic omics reveals that akebia saponin D attenuates neutrophil extracellular traps-induced neuroinflammation via NTSR1/PKAc/PAD4 pathway after intracerebral hemorrhage.
FASEB J
; 38(1): e23394, 2024 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38149910
4.
Rhizoma Paridis saponins attenuate Gram-negative bacteria-induced inflammatory acne by binding to KEAP1 and modulating Nrf2 and MAPK pathways.
J Cell Mol Med
; 28(6): e18146, 2024 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-38426932
5.
Anemoside B4 alleviates arthritis pain via suppressing ferroptosis-mediated inflammation.
J Cell Mol Med
; 28(4): e18136, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38334255
6.
Characterization of the cholesterol biosynthetic pathway in Dioscorea transversa.
J Biol Chem
; 299(6): 104768, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37142228
7.
Integrated evolutionary pattern analyses reveal multiple origins of steroidal saponins in plants.
Plant J
; 116(3): 823-839, 2023 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37522396
8.
DNA methylation regulates the secondary metabolism of saponins to improve the adaptability of Eleutherococcus senticosus during drought stress.
BMC Genomics
; 25(1): 330, 2024 Apr 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38565995
9.
Asperosaponin VI facilitates the regeneration of skeletal muscle injury by suppressing GSK-3ß-mediated cell apoptosis.
J Cell Biochem
; 125(1): 115-126, 2024 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38079224
10.
Enhanced extracellular vesicles mediated uttroside B (Utt-B) delivery to Hepatocellular carcinoma cell: Pharmacokinetics based on PBPK modelling.
Biochem Biophys Res Commun
; 703: 149648, 2024 Apr 09.
Artigo
Inglês
| MEDLINE | ID: mdl-38368675
11.
Paris saponin VII promotes ferroptosis to inhibit breast cancer via Nrf2/GPX4 axis.
Biochem Biophys Res Commun
; 697: 149524, 2024 Feb 19.
Artigo
Inglês
| MEDLINE | ID: mdl-38252991
12.
DT-13 inhibits the proliferation of pancreatic cancer by inducing apoptosis via AMPK-mTOR signaling.
Biochem Biophys Res Commun
; 695: 149451, 2024 Feb 05.
Artigo
Inglês
| MEDLINE | ID: mdl-38176173
13.
Integrated metabolome and transcriptome analyses reveal the molecular mechanism underlying dynamic metabolic processes during taproot development of Panax notoginseng.
BMC Plant Biol
; 24(1): 170, 2024 Mar 05.
Artigo
Inglês
| MEDLINE | ID: mdl-38443797
14.
Differential responses of two fenugreek (Trigonella foenum-graecum L.) landraces pretreated with melatonin to prolonged drought stress and subsequent recovery.
BMC Plant Biol
; 24(1): 161, 2024 Mar 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38429697
15.
Functional characterization of genes related to triterpene and flavonoid biosynthesis in Cyclocarya paliurus.
Planta
; 259(2): 50, 2024 Jan 29.
Artigo
Inglês
| MEDLINE | ID: mdl-38285114
16.
TMNP: a transcriptome-based multi-scale network pharmacology platform for herbal medicine.
Brief Bioinform
; 23(1)2022 01 17.
Artigo
Inglês
| MEDLINE | ID: mdl-34933331
17.
Blockade of PI3K/AKT signaling pathway by Astragaloside IV attenuates ulcerative colitis via improving the intestinal epithelial barrier.
J Transl Med
; 22(1): 406, 2024 Apr 30.
Artigo
Inglês
| MEDLINE | ID: mdl-38689349
18.
Mass spectrometry analysis of saponins.
Mass Spectrom Rev
; 42(3): 954-983, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-34431118
19.
Astragaloside IV-PESV inhibits prostate cancer tumor growth by restoring gut microbiota and microbial metabolic homeostasis via the AGE-RAGE pathway.
BMC Cancer
; 24(1): 472, 2024 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38622523
20.
Pulsatilla saponin D regulates ras-related C3 botulinum toxin substrate 3 (RAC3) to overcome resistance to paclitaxel in lung adenocarcinoma cells.
BMC Cancer
; 24(1): 55, 2024 Jan 10.
Artigo
Inglês
| MEDLINE | ID: mdl-38200409